Surgical oncology and reconstructionPediatric Ameloblastic Fibro-Odontosarcoma of the Mandible: A Challenge of Diagnosis and Treatment
Section snippets
Report of Case
A 6-year-old girl was referred to the authors' medical center from an eastern European country. Her medical records showed that, 3 years before her admission, an asymptomatic swelling surrounding the left mandible was observed. No further inquiry and treatment were performed at that time. As the facial deformation increased, the parents sought treatment. An incisional biopsy was obtained, with a diagnosis of AFOS. The patient received 3 courses of chemotherapy. No clinical improvement was noted
Discussion
The group of malignant odontogenic tumors consists of carcinoma and sarcoma variants and, very rarely, a carcinosarcoma variant. Malignant ameloblastoma retains a benign morphology but metastasizes. The malignant transformation of the epithelial component is observed in ameloblastic carcinoma, whereas the sarcomatoid transformation of the ectomesenchymal component is observed in AFS, ameloblastic fibrodentinosarcoma, and AFOS.2 In these sarcoma variants, the epithelial component is benign,
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A case of developing odontoma of the mandible with suspected BRAF p.V600E mutation
2023, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyReconstruction options in pediatric population with hemi or total mandibulectomy defects: A systematic review
2022, Journal of Oral Biology and Craniofacial ResearchCitation Excerpt :Quality assessment of individual case reports is presented in Table 1. A clear description of the demographics, intervention, adverse events and take-away message was provided by all the case reports.11,12,13,14,15,16,17,18,19,20,21,22,2,23 Maximum articles reported the patient's history14,15,16,17,19,20,21 and clinical presentation adequately.14,15,16,17,19,20,21,22
Ameloblastic fibrodentinosarcoma and ameloblastic fibro-odontosarcoma: A systematic review
2018, Journal of Stomatology, Oral and Maxillofacial SurgeryCitation Excerpt :Thus, a total of 17 publications were included in the review . Seventeen publications reporting 8 AFDS [2,7–13] and 9 AFOS [14–22] were included in the present review. Table 1 presents the details of each case separately.
Ameloblastic fibro-odontoma: Case report and immunohistochemical profile
2017, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAmeloblastic fibro-odontosarcoma of the mandible in a pediatric patient
2016, European Annals of Otorhinolaryngology, Head and Neck DiseasesAmeloblastic fibrodentinosarcoma: a rare malignant odontogenic tumor
2016, Brazilian Journal of Otorhinolaryngology