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Journal Information
Issue
Vol. 92. Issue 2. (In progress)Vol. 92. Issue 2. (In progress)
(March - April 2026)
This issue is in progress but contains articles that are final and fully citable.
Editorials
Hidden in plain sight: why diagnosing asymptomatic congenital cytomegalovirus (cCMV) changes everything
Vagner Antonio Rodrigues Silva, Nicolau Moreira Abrahão, Arthur Menino Castilho
Braz J Otorhinolaryngol. 2026;92:
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Original articles
Combined endoscopic and open frontolateral laryngectomy for glottic tumors involving the anterior commissure
Leonardo Haddad, Fabio Pupo Ceccon, Leticia Angélica da Silva Souza, Beatrice Haase Ceccon, João Vitor Pincelli, Mateus Morais Aires
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • Combined approach enables precise resection of AC-involving glottic tumors.

  • Technique ensures oncologic safety with minimal healthy tissue removal.

  • Vocal fold reconstruction may enhance phonatory outcomes.

  • No cases of permanent tracheostomy or postoperative dysphagia.

  • Careful patient selection is key to optimizing outcomes.

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miR-199a-5p inhibits malignant progression and enhances cisplatin sensitivity of nasopharyngeal carcinoma by targeting SLC1A5
Anchi Sun, Rongrong Lv, Zhiwei Xing, Yifan He, Xiaomin Wang, Hui Li, Qianqian Shao
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • MiR-199a-5p was lowly expressed in NPC.

  • Low expression of miR-199a-5p is associated with a poorer prognosis.

  • MiR-199 can increase the sensitivity of NPC to cisplatin resistance.

  • MiR-199a-5p directly targets SLC1A5 to negatively regulate its expression.

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P16INK4a protein expression associated with Head and Neck Squamous Cell Carcinoma: A perspective of a public health reference service in São Paulo
Mariah Cristina Antunes do Nascimento, Ana Lívia Silva Galbiatti-Dias, Lucas Brumato Figueiredo, Ludimila Leite Marzochi, Márcia Maria Urbanin Castanhole-Nunes, Rafael Felipe Maciel Andrade, José Victor Maníglia, Lilian Castiglioni, ... Eny Maria Goloni-Bertollo
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • The p16INKa protein in head and neck cancer patients indicates HPV involvement.

  • Patients HPV-positive cancer often leads to the development of distant metastases.

  • Patients HPV-negative cancer often leads to the development of locoregional recurrence.

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Explainable machine learning model for predicting hearing recovery in unilateral sudden sensorineural hearing loss
Jueting Wu, Ruru Chen, Yaxuan Liu, Feng Zhao, Huiying Chen, Xiaoyu Lin, Jiping Su
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • Explainable ML performed well in predicting hearing recovery in SSNHL patients.

  • The RF model performed best among the ML models

  • The most primary feature was degree of hearing loss.

  • MCV was found to be an pivotal factor for the first time.

  • The SHAP method help clinicians to better understand the features in ML models.

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Association of triglyceride and cholesterol with vestibular vertigo: Evidence from univariable and multivariable mendelian randomization and mediation analysis
Ying Mu, Yacheng Lu, Wei Fu
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • Triglyceride and cholesterol are causally associated with vestibular vertigo.

  • Vitamin D mediated the causal effect of cholesterol on vestibular vertigo.

  • Vitamin D supplement may be helpful treatment of vestibular vertigo.

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Discriminative validity and diagnostic accuracy of Horus® posturographic parameters in individuals with and without vestibulopathy
Maria Clara Peixoto Marinheiro, Ana Clara Teixeira Fernandes, Luana Dantas da Silva, Adriana Guedes Carlos, José Diniz Júnior, Juliana Maria Gazzola, Vanessa Regiane Resqueti
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • CE/SL and MV/ML in C4 are effective for ruling out vestibular dysfunction.

  • Vestibular Function and CBI show high sensitivity in vestibular disorder diagnosis.

  • Moderate to large differences were observed for Visual Function, Vestibular, and CBI.

  • Horus® parameters enhance vestibular dysfunction diagnosis and rehabilitation.

  • Posturographic parameters showed moderate-to-good discriminative validity.

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Image-guided protocol with a guide-marker for bone conduction hearing implant placement estimation
Renata Tadeu Ramirez Garcia, Antonio Carlos dos Santos, Fabiana Danieli-Hyppolito, Miguel Angelo Hyppolito
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • Image-guided implant placement estimation was effective to install BCHI.

  • The proposed protocol proved to be replicable in clinical practice.

  • Relevant findings were identified in 52.9% of subjects, impacting implant placement in 37.3% of cases.

  • The proposed protocol may increase the safety and efficacy of BCHD surgery.

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Nomogram for predicting cognitive impairment in middle-aged and elderly individuals with self-reported hearing loss: Insights from the longitudinal CHARLS cohort
Cheng Li, Yan Mei, Wei Li, Dan Liu
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • A nomogram predicts cognitive decline in self-reported hearing-impaired older adults.

  • Education, urban living, and social activity are key protective factors.

  • The model shows good performance (AUC 0.728–0.768; C-index >0.71).

  • Risk scores differ significantly across demographic subgroups.

  • The nomogram facilitates early identification and targeted prevention.

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An affordable and optimized 3D biomodel for sinonasal surgery training
Marcelo Augusto Antonio, Sergio Lopes Fernandes Ramos, Fernando Augusto Lima Marson, Mariana Dalbo Contrera Toro, Eulalia Sakano
Braz J Otorhinolaryngol. 2026;92:
Highlights

  • An affordable set was developed for endonasal surgical training.

  • Senior rhinologists rated its anatomical accuracy and haptics as realistic.

  • The set offers a practical solution for repetitive surgical practice.

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Case reports
Bilobed flap for lower lip reconstruction: A two-case series and technical considerations
Victor Bandini Vieira, Giovana Cruz Corsi, Rafael Pereira de Souza, Rafael De Cicco
Braz J Otorhinolaryngol. 2026;92:
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Brazilian Journal of Otorhinolaryngology (English Edition)
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