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Journal Information
Issue
Cover Vol. 92. Issue 3. Vol. 92. Issue 3.
(May - June 2026)
Editorials
Moving past the usual suspects: a new framework for aural fullness
Roseli Saraiva Moreira Bittar, Lucas Resende Lucinda Mangia, Raquel Mezzalira
Braz J Otorhinolaryngol. 2026;92:
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Rethinking What We Call “Reflux”: A Call for Critical Reappraisal in Brazilian Otolaryngology
Adriana Hachiya, Paulo Lins Perazzo, Luciana Miwa Nita Watanabe, André Alencar Araripe Nunes
Braz J Otorhinolaryngol. 2026;92:
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Original articles
Glottoplasty for vocal feminization in transgender women: position paper of the Brazilian Academy of Laryngology and Voice (ABLV)
Mateus Morais Aires, André Alencar Araripe Nunes, Érica Cristina Campos e Santos, Christiano de Giacomo Carneiro, Guilherme Simas do Amaral Catani, Adriana Hachiya, Erik Frota Haguette, Luciano Rodrigues Neves, ... Marcos André de Sarvat
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Consensus-based recommendations using modified Delphi methodology.

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    Clear surgical indications and contraindications were established.

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    Comprehensive perioperative care recommendations are provided.

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    Surgical indication prioritizes vocal gender incongruence, not acoustic measures.

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    Most recommendations rely on low-grade evidence (case series and expert opinion).

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Prognostic significance of minimal extrathyroidal extension in differentiated thyroid carcinoma: a retrospective cohort study
Beatriz G. Cavalheiro, Vergilius José Furtado de Araújo Filho, Leandro Luongo Matos, Ana Kober Leite, Claudio Roberto Cernea, Luiz Paulo Kowalski
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Minimal ETE is associated with adverse risk features in thyroid carcinoma.

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    Patients with minimal ETE had higher recurrence rates in univariate analysis.

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    Minimal ETE was not an independent predictor of poor outcomes.

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    Risk stratification should not rely solely on the presence of minimal ETE.

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A bioinformatics analysis revealing autophagy related DEGs in head and neck squamous cell carcinoma: expanding insights into lipid metabolism
Yi Cheng, Xiaoyu Li
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    A successful establishment of a prognostic model for head and neck tumors.

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    Differential autophagy genes in tumor models.

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    A bioinformatics analysis about head and neck squamous cell carcinoma.

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Triamcinolone acetonide for aesthetic refinement in rhinoplasty for patients with thick skin: the FAN technique ‒ a pilot study
Ali Abdullah Alshehri
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    ROE and VAS scores significantly improve post-injection.

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    Single TA injection using FAN technique ensures even drug distribution.

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    FAN technique provides safe, minimally invasive TA delivery.

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    Tailored TA regimen offers sustained benefits in thick-skinned patients.

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Severe and profound hearing loss in patients with multiple sensory impairments: increased incidence of cognitive impairment
Jacob C. Lucas, Alexandra M. Arambula, Katherine Yu, Linda D’Silva, Jennifer A. Villwock, Hinrich Staecker
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Combined sensory dysfunction increased the odds of cognitive impairment.

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    More severe hearing loss increased the likelihood of cognitive impairment.

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    Patients with hearing loss should be screened for other sensory disorders.

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Atopic dermatitis and chronic sinusitis: a two-sample Mendelian randomized study
Jian Luo, Yuanzhi Zhu, Yuting Zhang, Kai Zhang
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Mendelian analysis reveals genetic association between AD and CRS.

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    No reverse genetic association detected from CRS toward AD.

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    Results support shared inflammatory pathways in AD and CRS.

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Long COVID-19 olfactory dysfunction: discrepancy between psychophysical tests and self-perception
Aina Sansa, Alda Cardesín, Mariana Campos, Carlota Rovira, Josep de Haro, Elios Yuste, Miguel Caballero-Borrego
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Many COVID-19 patients experience olfactory dysfunction.

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    Self-reported olfactory complaints often do not match the results of smell tests.

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    Long COVID shows a predominantly identification-dominant olfactory impairment.

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    Recognizing key features helps refine diagnosis and guide targeted treatment.

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Zetapalatopharyngoplasty in treatment of obstructive sleep apnea: a 10-year retrospective study
Alan Rodrigues de Almeida Paiva, Mauro Becker Santos Vieira, Roberto Eustáquio Santos Guimaraes, Ana Paula Alves Pereira, Yuri Alexandre Mota Amaral, Maria Clara Argolo Costa, Nayane Oliveira Pio
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    ZPFP surgery significantly reduced AHI and T90 scores, improving OSA severity.

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    A 10-year follow-up period evaluating palatoplasty outcomes.

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    Patients demonstrated significant enhancements in SAQLI and ESS scores.

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    Postoperative ZPFP complications were mild, with no mortality or severe adverse events.

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    Patients’ non-adherent to CPAP benefited significantly from ZPFP surgical intervention.

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Comparison of utility measures and auditory performance in children with cochlear implants and hearing aids in India: a cross-sectional study
Anuradha Sharma, Shankar Prinja, Ravinder Thakur, Rajwinder Kaur, Sanjay Munjal, Jaimanti Bakshi
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    First Indian study to evaluate long-term QOL outcomes in CI and HA children.

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    Multi-tool analysis reveals cochlear implants greatly outperform hearing aids.

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    HUI-3 effectively captures hearing-related QOL gains missed by EQ-5D.

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    Functional auditory outcomes strongly linked to improved health utility scores.

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    Robust evidence supporting CI as the superior intervention for paediatric deafness.

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Tomographic assessment of anatomical boundaries in endoscopic frontal sinusotomy: retrospective radiologic analysis of Draf IIA and IIB approaches
Paulo José da Costa Mariz Neto, Camila de Santa Cruz Souza, Matheus Dorigatti Soldatelli, Rainer Guilherme Haetinger, Eduardo Macoto Kosugi, Thiago Freire Pinto Bezerra
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    CT-based measurements guide safer and more effective frontal sinus surgeries.

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    First study to objectively measure drainage gain in Draf frontal sinusotomy.

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    Incomplete beak removal compromises surgical success in frontal sinusotomy.

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    Draf IIB is only effective with full frontal beak removal.

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    Complete removal of the frontal beak triples frontal sinus drainage pathway.

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Neurodegeneration of the mastoid segment of the human facial nerve associated with senescence
Ivam Luiz Mariano Rocha, Joel Lavinsky, Mateus Belmonte Macedo, Adriana Ubirajara Silva Petry, Taís Malysz
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    There was a progressive reduction in myelination of the facial nerve with aging.

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    Reduction in the cross-sectional area of facial nerve axons occurs at older ages.

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    Increase in the quantity of small myelin fibers at older ages.

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    Decrease in the quantity of large myelin fibers at older ages.

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    The number and density of nerve fibers were not altered during aging.

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Elevated S100A8 in nasal mucosa correlates with epithelial barrier dysfunction in allergic rhinitis
Xiaocong Deng, Di Wu, Zhenlin Cai, Yong Qian
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    S100A8 is upregulated in AR and correlates with disease severity.

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    S100A8 negatively regulates tight junction proteins in the nasal epithelium.

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    Knocking down S100A8 restores the barrier integrity in HDM-exposed HNECs.

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Cross-cultural validation of the SNOT-22 questionnaire in the Colombian population
Susana Soto-Tirado, Silvia Nicté Villatoro-Rodríguez, Tania Margarita Salgado, Lina Paola Londoño-Martínez, Benjamín Darío Ariza de la Ossa, Juan David Bedoya-Gutiérrez
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Culturally adapted the SNOT-22 for Colombian patients with expert input.

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    High internal consistency: Cronbach’s α = 0.97, omega = 0.96.

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    Strong correlation with symptom severity (VAS, Spearman r = 0.74).

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    Effectively discriminate patients with and without rhinosinusitis.

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    High diagnostic accuracy: AUC = 0.92, sensitivity = 71.5%.

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Identification of hypoxia-related gene signatures and molecular subtypes in chronic rhinosinusitis with nasal polyps
Lulu Song, Shican Zhou, Lili Wang, Ju Lai, Shiwang Tan, Chunyan Yao, Shaoqing Yu
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    This study identifies four genes as potential biomarkers for CRSwNP.

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    Machine learning techniques were used to effectively identify key genes.

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    Clustering analysis reveals two distinct molecular subtypes of CRSwNP.

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    This study identified sensitive drugs with therapeutic potential for two clusters.

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Assessing the quality of life and subjective ratings of the anatomy-based fitting map among experienced, adult cochlear implant users
Pelden Wangchuk, Cila Umat, Chong Foong Yen, Faizah Mohd Zaki, Asma Abdullah
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Anatomy-based fitting is relatively a new cochlear implant mapping technique.

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    Frequency-to-place mismatch is addressed by Anatomy-based fitting.

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    Quality of life improved after using an anatomy-based fitting method for 6-months.

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    Enhanced subjective feedback.

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    Improved vowel recognition in quiet is strongly linked with improved enjoyment of entertainment domain in CIQoL-35.

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Impact of hearing aid use on cognitive function in elderly individuals with hearing loss: a prospective study
Henrique Cannever Velho, Murilo Aparecido Sanches Cruz Schichi, Tyuana Sandim da Silveira Sassi, Jerusa Roberta Massola de Oliveira, Rubens Neto, Luiz Fernando Manzoni Lourençone
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Auditory stimulation may modulate cognitive function in older adults.

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    Cognitive scores improved after 6- and 12-months of hearing aid use.

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    Greater cognitive benefits were observed in participants with prior decline.

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    Verbal fluency and visuospatial skills showed significant post-HA gains.

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    Hearing aids reduced self-perceived auditory handicap over time.

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Review articles
Is there any relationship between the menopause transition and dizziness?
Lucas Resende Lucinda Mangia, Roseli Saraiva Moreira Bittar
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    The literature shows the impact of female sex hormones on the nervous system.

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    Estradiol acts to modulate physiological functions related to vestibular activity.

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    There is a high prevalence of vestibular symptoms and diseases in midlife women.

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    Hormonal changes in menopause transition influence specific vestibular disorders.

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    Understanding how menopause affect vestibular patients may help improve their care.

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Validation of self-hearing test in non-clinical setting: a systematic literature review
Nor Hidayah Mohammed Hatta, Wan Najibah Wan Mohamad, Mohd Normani Zakaria, Mohd Fadzil Nor Rashid, Mohd Syaiful Nizam Abu Hassan, Hasrul Hosshan
Braz J Otorhinolaryngol. 2026;92:
Highlights

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    Automated audiometry achieves 71%–98.5% accuracy in nonclinical settings.

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    Smartphone hearing screenings are 12.3% faster than conventional methods.

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    Automated self-hearing tests are promising for early detection in children.

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    Automated audiometry delivers reliable audiograms and reducing costs.

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    Automated audiometry improves hearing healthcare access, valid and reliable.

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Case reports
Lipoma in the hypopharynx: a case report
Diego Guzman Rodrigues, Rynat Dasaev Oliveira Chagas, Natália Matos Muricy, Raissa Damasceno Barreto da Silva
Braz J Otorhinolaryngol. 2026;92:
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Experience of comprehensive sequential therapy for salivary duct carcinoma with HER2 gene amplification: a case report
Yu Zhang, Chenke Wei, Wei Shang, Zongxuan He
Braz J Otorhinolaryngol. 2026;92:
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Letters to the editor
Letter to the Editor Regarding “Alterations of gut microbiome in chronic rhinosinusitis: insights from a mendelian randomization study”
Rafael Gomes de Melo D’Elia, Angélica Saiuri de Aurélio Penteado
Braz J Otorhinolaryngol. 2026;92:
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Epistaxis kit ‒ a standardized approach to optimize emergency care
Luciano Lobato Gregorio, Eduardo Macoto Kosugi
Braz J Otorhinolaryngol. 2026;92:
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Brazilian Journal of Otorhinolaryngology (English Edition)