Journal Information
Vol. 88. Issue S3.
Pages S1-S234 (November - December 2022)
Original articles
The circadian timing of noise exposure influences noise-induced inflammatory responses in the mouse cochlea
Shichang Li, Hongwei Zheng, Zhimin Xing, Yan Liu, Lin Han, Zijing Wang, Lisheng Yu
Braz J Otorhinolaryngol. 2022;88 Supl 3:S1-S8

  • A 1-hr exposure to 6∼12 kHz noise at 100 dB SPL could cause a temporary threshold shift in C57BL/6J mice without hair cell loss.

  • The circadian timing of noise exposure did not affect ABR threshold shifts.

  • The circadian timing of noise exposure influences noise-induced inflammatory responses in the mouse cochlea.

  • Daytime noise may induce a greater inflammatory response than that of nighttime noise.

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Determining attributed factors of hearing handicap in individuals with auditory sensory and neural pathology
Sindhu Parthasarathy, Hemanth Narayan Shetty
Braz J Otorhinolaryngol. 2022;88 Supl 3:S9-S19

  • The study investigates the effect of site of lesion on the contributory factors of hearing handicap.

  • The study provides insight into how much the mild ANSD subject suffers against their counterparts who have a sensory impairment.

  • The finding purports that “mild” ANSD subjects have listening impairment similar to that of “severe” degree of SNHL subjects.

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Congenital syphilis associated with hearing screening failure in southern Brazilian newborns
Eduarda Besen, Karina Mary Paiva, Danúbia Hillesheim, Luciana B. Cigana, Patrícia Haas
Braz J Otorhinolaryngol. 2022;88 Supl 3:S20-S24

  • Hearing is one of the key senses for humans overall development.

  • Hearing loss, which is a decrease in the ability to detect speech and environmental sounds, may be attenuated if detected.

  • In Brazil, the incidence of congenital syphilis in 2019 was 9.0/1000 live births, and its mortality rate was 8.2/100,000 live births.

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Effects of vestibular rehabilitation in the management of patients with and without vestibular migraine
Ahmet Koc, Elvan Cevizci Akkılıc
Braz J Otorhinolaryngol. 2022;88 Supl 3:S25-S33

  • Vestibular Migraine (VM) is the second most common cause after Benign Paroxysmal Positional Vertigo in patients with vertigo.

  • Drugs used in migraine headaches are also used in the treatment of VM, but complaints of dizziness/vertigo may progress.

  • Vestibular Rehabilitation (VR) provide significant improvement in vestibular symptoms and quality of life in VM patients.

  • VR should be considered in addition to medical treatment in patients with vestibular migraine.

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The clinical features and image characteristics of Meniere's disease patients with endolymphatic hydrops confirmed by enhanced magnetic resonance imaging
Wei Chen, Xiao Wu, Yue Geng, Naier Lin, Yan Sha
Braz J Otorhinolaryngol. 2022;88 Supl 3:S34-S40

  • 3D-real IR MRI can provide a better assessment of EH in MD patients.

  • Including EH in the diagnostic criteria can increase the MD diagnosis rate.

  • The EH degree or distribution may be related to the degree of hearing loss.

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Effectiveness of conventional versus virtual reality-based vestibular rehabilitation exercises in elderly patients with dizziness: a randomized controlled study with 6-month follow-up
Tuba Kanyılmaz, Oya Topuz, Fazıl Necdet Ardıç, Hakan Alkan, Saadet Nur Sena Öztekin, Bülent Topuz, Füsun Ardıç
Braz J Otorhinolaryngol. 2022;88 Supl 3:S41-S49

  • Vestibular rehabilitation supported with virtual reality appears to be effective in elderly patients with dizziness.

  • Virtual reality-based vestibular rehabilitation is superior to conventional vestibular rehabilitation therapy alone.

  • The implementation of the virtual reality environment in the vestibular rehabilitation program may be useful.

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Is there a change in P300 evoked potential after 6 months in cochlear implant users?
Maria Stella Arantes do Amaral, Victor G. Calderaro, Henrique Furlan Pauna, Eduardo T. Massuda, Ana Cláudia. M.B. Reis, Miguel Angelo Hyppolito
Braz J Otorhinolaryngol. 2022;88 Supl 3:S50-S58

  • The lowest latency of P3 occurred six months after CI-activation for the tone burst stimulus.

  • The lowest latency of P3 occurred Pre-CI with speaking stimulus.

  • There was a poor correlation between the mean latency of P3 and the time of hearing loss for the speech stimulus.

  • There was no variation of the P3 amplitude after 6 months using cochlear implant.

  • There was an increase of P3 latency in individuals older than 45 years, for both puretone and speech stimuli.

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The effect of noise on the amplitude and morphology of cortical auditory evoked potentials
Danielle Samara Bandeira Duarte, Silvana Maria Sobral Griz, Mônyka Ferreira Borges Rocha, Diana Babini Lapa de Albuquerque Britto, Denise Costa Menezes, Karina Paes Advíncula
Braz J Otorhinolaryngol. 2022;88 Supl 3:S59-S65

  • The presence of masking noise interferes with latency and amplitude measurements of Cortical Auditory Evoked Potentials.

  • Presence of forward masking phenomenon during the measurements in the masking noise presentation condition before the speech stimulus.

  • Greater presence of forward masking phenomenon in the elderly group.

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Effectiveness of galvanic vestibular evoked myogenic potential for evaluation of Meniere’s disease
Ying Cheng, Yuzhong Zhang, Zichen Chen, Weijun Ma, Yanfei Chen, Qing Zhang, Min Xu
Braz J Otorhinolaryngol. 2022;88 Supl 3:S66-S72

  • GVS and ACS-VEMPs were compared in patients with unilateral MD and normal controls.

  • GVS was as effective as ACS for inducing VEMPs, and even faster than ACS.

  • GVS-VEMP recording can detect retrolabyrinthine degeneration in MD.

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Astaxanthin protects against hearing impairment in diabetic rats
Serdar Ferit Toprak, Serkan Dedeoğlu
Braz J Otorhinolaryngol. 2022;88 Supl 3:S73-S80

  • Diabetes mellitus causes an increase in oxidative stress that leads to deterioration in auditory functions.

  • Astaxanthine is known to have strong antioxidant effects.

  • The results show that Astaxanthine has protective effects against hearing impairment due to DM with its antioxidant and anti-inflammatory properties.

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Vestibular function assessment in sudden hearing loss
Nathalia de Paula Doyle Maia, Karen de Carvalho Lopes, Fernando Freitas Ganança
Braz J Otorhinolaryngol. 2022;88 Supl 3:S81-S88

  • Vestibular involvement in sudden hearing loss was very frequent (88.23%).

  • The ocular vestibular evoked myogenic potential was the most frequently altered vestibular test.

  • The vestibular test results were not related to hearing prognosis.

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Complex benign horizontal canal positional vertigo: new perceptual management
Narendra B. Suratwala, Jay N. Suratwala, Madhav V. Bapat
Braz J Otorhinolaryngol. 2022;88 Supl 3:S89-S94

  • The maiden HPE report of HSC pathology improves the understanding of etiology of BPPV.

  • The quick head rotational test using gravity complements Dix-Hallpike test and is more effective in locating cupular and anterior arm pathology of HSC.

  • Modified II stage of Semont’s maneuvere using utmost gravity force clears the cupolar deposits more efficiently than concurrent therapies.

  • The proposed protocol in managing HSC BPPV of complex presentation is found to be extremely useful in clinical practice in a busy vertigo clinic.

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The effect of increase in blood glucose level on hearing loss
Guven Akcay, Betul Danısman, Goksun Basaranlar, Pınar Guzel, Narin Derin, Alper Tunga Derin
Braz J Otorhinolaryngol. 2022;88 Supl 3:S95-S102

  • Diabetes is a disease caused by insulin deficiency.

  • Lipid peroxidation plays an important role in the pathogenesis diabetes mellitus.

  • Diabetes mellitus leads to sensorineural hearing loss.

  • Regulation of blood glucose level may prevent hearing loss in diabetic people.

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Melatonin prevents age-related hearing loss in the murin experimental model
Lucieny Silva Martins Serra, Juliana Gusmão de Araújo, Gabriela Novanta, Lucas Lauand, Eduardo Magalhães da Silva, Selma Aparecida Souza Kückelhaus, André Luiz Lopes Sampaio
Braz J Otorhinolaryngol. 2022;88 Supl 3:S103-S108
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Translation and validation of the Tinnitus Primary Function Questionnaire into Brazilian Portuguese
Patrícia Perez Coradini, Sabrina Nuñes Gonçalves, Jeanne Oiticica
Braz J Otorhinolaryngol. 2022;88 Supl 3:S109-S116

  • The translated version of the Tinnitus Primary Function Questionnaire showed good test-retest accuracy with robust interclass correlation coefficient values.

  • The Brazilian version of the Tinnitus Primary Function Questionnaire showed high reliability according to the results of Cronbach’s alpha.

  • Pearson’s correlation coefficient demonstrated a strong correlation between the total scores of Tinnitus Primary Function Questionnaire and Tinnitus Handicap Inventory scores.

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Audio-vestibular and radiological analysis in Meniere’s disease
Arzu Kirbac, Saziye Armagan Incesulu, Ugur Toprak, Hamdı Caklı, Hulya Ozen, Suzan Saylisoy
Braz J Otorhinolaryngol. 2022;88 Supl 3:S117-S124

  • IV Gd-enhanced inner ear MRI (EH + PE) had higher sensitivity and specificity than the vestibular test battery.

  • Among the vestibular tests, the highest sensitivity and specificity were obtained from the caloric test.

  • In suspected MD, the clinical history, hearing tests, MRI (EH+PE) are sufficient for diagnosis in certain patient groups.

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The Portuguese version of the visual vertigo analog scale
Ana Margarida Amorim, João Simões, Joana Gonçalves, Mafalda Ferreira, João Carlos Ribeiro
Braz J Otorhinolaryngol. 2022;88 Supl 3:S125-S129

  • Visual vertigo occurs after a vestibular disorder compromising daily living.

  • Visual vertigo analog scale is reliable to be used in the Portuguese population.

  • Visual vertigo is severe across all kinds of vestibular syndromes.

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Changes in late-latency auditory evoked potentials after tinnitus suppression using auditory stimulation
Nastaran Ranjbar, Ali Shahbazi, Hossein Namvar Arefi, Navid Noori Zade, Mohammad Ali Nazari, Sadegh Jafarzad
Braz J Otorhinolaryngol. 2022;88 Supl 3:S130-S138

  • Late-latency auditory evoked potentials changes after tinnitus suppression.

  • The N1, P3a, and P3b were significantly changed in tinnitus subjects.

  • The P3a changes after short-term auditory stimulation in tinnitus subjects.

  • The N1 latency decreases after long-term use of tinnitus masker.

  • Our findings supports a common mechanism for residual inhibition and tinnitus masker.

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Effect of age on virtual reality-assisted subjective visual vertical and subjective visual horizontal at different head-tilt angles
Ying Cheng, Yuzhong Zhang, Weijun Ma, Yanfei Chen, Qing Zhang, Min Xu
Braz J Otorhinolaryngol. 2022;88 Supl 3:S139-S146

  • VR-assisted SVV and SVH data at different head-tilt angles were established.

  • Age may not affect VR-assisted SVV and SVH values at different head-tilt angles.

  • VR-assisted SVV and SVH tests are an effective way to evaluate utricle function.

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Clinical characteristics of definite vestibular migraine diagnosed according to criteria jointly formulated by the Bárány Society and the International Headache Society
Zhe-Yuan Li, Bo Shen, Li-Hong Si, Xia Ling, Kang-Zhi Li, Xu Yang
Braz J Otorhinolaryngol. 2022;88 Supl 3:S147-S154

  • Definite Vestibular Migraine (dVM) is more common in women.

  • The onset of migraine precedes that of vestibular symptoms, which are often accompanied by photophobia and phonophobia.

  • Most patients develop motion sickness and cannot tolerate the caloric test, which can contribute to dVM diagnosis.

  • Motion sickness and severe caloric test intolerance can contribute to the diagnosis of dVM.

  • Immunological indicators are abnormal in some patients with dVM.

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The reliability and validity of decreased sound tolerance scale-screening
Serpil Allusoglu, Songul Aksoy
Braz J Otorhinolaryngol. 2022;88 Supl 3:S155-S163

  • Decreased Sound Tolerance Scale-Screening is easy to apply and takes a short time.

  • This scale distinguishes hyperacusis, phonophobia, misophonia.

  • This scale guides clinician to which discipline the patient should be referred.

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Hearing aid effectiveness on patients with chronic tinnitus and associated hearing loss
Patricia Simonetti, Laura Garcia Vasconcelos, Mara Rocha Gândara, Karina Lezirovitz, Ítalo Roberto Torres de Medeiros, Jeanne Oiticica
Braz J Otorhinolaryngol. 2022;88 Supl 3:S164-S170

  • Amplification restores auditory input and reduce tinnitus annoyance.

  • THI reduction has been considered to be clinically and statistically significant after 6-months of hearing aid usage.

  • A significant reduction in THI and VAS indicates a significant improvement in tinnitus severity.

  • Minimal masking levels showed statistically significant reduction after 6-months use of HA, and inverse correlation with duration of tinnitus.

  • THI, HHIA, VAS for tinnitus annoyance and MMLs are interrelated parameters on tinnitus amelioration.

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Analysis of clinical parameters as predictors of hearing recovery in patients with sudden sensorineural hearing loss
Nikola Kolja Poljak, Marisa Klančnik, Petar Ivanišević, Petra Mikulić, Marta Zrinka Vucemilovic
Braz J Otorhinolaryngol. 2022;88 Supl 3:S171-S176

  • Sudden sensorineural hearing loss is defined as a sensoneural hearing loss of at least 30 decibels, which affects at least three consecutive frequencies within 72hours.

  • The etiology of SSNHL is fairly unknown, and so, it is often referred to as an idiopathic disease.

  • Sudden sensorineural hearing loss requires immediate treatment.

  • Tonal audiometry results, diabetes mellitus and onset of therapy were shown to be a statistically significant negative predictive factors for recovery.

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The clinical application of head-shaking test combined with head-shaking tilt suppression test in distinguishing between peripheral and central vertigo at bedside vs. examination room
Huiying Sun, Yinping Wang, Hong Jiang, Zhiqiang Gao, Haiyan Wu
Braz J Otorhinolaryngol. 2022;88 Supl 3:S177-S184

  • Combined HST and the HSTS test have a higher specificity than HST alone.

  • Repressible horizontal HSN usually suggests a peripheral vertigo specifically.

  • Findings of the bedside HST+HSTST are consistent with those of VNG.

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Otoneurological assessment and quality of life of individuals with complaints of dizziness and temporomandibular disorders: a case-control study
Mônica Claudino Medeiros Honorato, Luiz Felipe Tavares, Henrique de Paula Bedaque, Erika Barioni Mantello, Erika Oliveira de Almeida, Karyna Myrelly Oliveira Bezerra de Figueiredo Ribeiro, Lidiane Maria de Brito Macedo Ferreira
Braz J Otorhinolaryngol. 2022;88 Supl 3:S185-S191

  • Aural fullness and otalgia symptoms are associated with temporomandibular disorders in patients with dizziness.

  • Patients with dizziness and without temporomandibular disorders have a greater impact on quality of life.

  • The most affected quality of life domains are the functional and emotional ones.

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Review articles
Ocular findings from otoneurological examinations in children with and without dyslexia: a systematic review with meta-analysis
Ysa Karen dos Santos Macambira, Jessyca Vanessa dos Santos Barbosa, Bianca Manchester de Queiroga, Ana Augusta de Andrade Cordeiro, Denise Costa Menezes, Maria Luiza Lopes Timóteo de Lima, Karina Paes Advíncula
Braz J Otorhinolaryngol. 2022;88 Supl 3:S192-S201

  • Vestibular evaluation of children with dyslexia.

  • Ocular evidence of otoneurology in dyslexia.

  • The measurements of ocular tests in children with dyslexia.

  • Vectoelectro-nystagmography and videonystagmography exams in children with dyslexia.

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Galvanic vestibular stimulation and its applications: a systematic review
Anna Paula Batista de Ávila Pires, Tatiana Rocha Silva, Maíra Soares Torres, Maria Luiza Diniz, Maurício Campelo Tavares, Denise Utsch Gonçalves
Braz J Otorhinolaryngol. 2022;88 Supl 3:S202-S211

  • Galvanic vestibular stimulation is used for peripheral and central vestibular rehabilitation.

  • Galvanic vestibular stimulation partially or totally improves body balance.

  • Galvanic vestibular stimulation has also therapeutic application in cognition and mood.

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Vestibular assessment in children aged zero to twelve years: an integrative review
Danielle Samara Bandeira Duarte, Anna Marial de Lira Cabral, Diana Babini Lapa de Albuquerque Britto
Braz J Otorhinolaryngol. 2022;88 Supl 3:S212-S224
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Hearing and language development in children with brainstem implants: a systematic review
Quemile Pribs Martins, Bruna de Franceschi Schirmer Gindri, Cristiane Dellinghausen Valim, Laís Ferreira, Fernanda Soares Aurélio Patatt
Braz J Otorhinolaryngol. 2022;88 Supl 3:S225-S234

  • Language development is progressive.

  • All children acquired basic auditory perception skills.

  • Evolution of word identification up to sentence recognition level.

  • Alternative to children born with cochlear malformation or auditory nerve deficiency.

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Brazilian Journal of Otorhinolaryngology (English Edition)
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